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In vitro ADME Studies
The generation of rapid, high-quality in vitro ADME data in the early phases of drug discovery is a critical component of chemical design, providing an understanding of the metabolic liability, disposition and safety profile of novel compounds. Using our expertise and experience of ADME science in support of drug discovery we can provide generic high-throughput assays or develop bespoke in vitro experiments to meet specific requirements. High sensitivity UHPLC-MS/MS systems and Hamilton Microstar robotic instrumentation enhance the consistency and throughput of ADME assays to provide robust, rapid and reproducible results.
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